मुख्यमंत्री पुष्कर सिंह धामी ने गुरुवार को टनकपुर के छीनीगोठ में आयोजित “मुख्यमंत्री सशक्त बहना उत्सव” में प्रतिभाग कर महिलाओं के आत्मविश्वास, उद्यमशीलता और पारंपरिक कौशल का उत्सव मनाया।
कार्यक्रम में पहुंचने पर मुख्यमंत्री ने महिलाओं और बेटियों के उत्साह को देखकर प्रसन्नता व्यक्त की। उन्होंने कहा कि “महिलाओं की भागीदारी से ही ‘विकसित उत्तराखण्ड’ का सपना साकार होगा। राज्य सरकार महिलाओं को केवल सहयोग नहीं दे रही, बल्कि उन्हें सशक्त और आत्मनिर्भर बनाने के लिए प्रतिबद्ध है।”
मुख्यमंत्री धामी ने उत्सव स्थल पर लगे विभिन्न लाइव स्टालों का अवलोकन किया और महिलाओं के श्रम व कौशल को प्रत्यक्ष रूप से अनुभव किया। उन्होंने न केवल प्रदर्शनी देखी, बल्कि महिलाओं की गतिविधियों में स्वयं भाग लेकर उन्हें प्रेरित किया।
मुख्यमंत्री धामी ने एक स्टाल पर जाकर महिलाओं के साथ पारंपरिक तरीके से मट्ठा बनाने की प्रक्रिया में भाग लिया। उन्होंने कहा कि पारंपरिक खाद्य पदार्थ हमारी संस्कृति और स्वास्थ्य दोनों से जुड़े हैं, इन्हें आधुनिक रूप में बाजार से जोड़ना समय की मांग है।
इलेक्ट्रिक कार्यों में संलग्न महिलाओं के स्टाल पर पहुंचकर मुख्यमंत्री ने महिलाओं के साथ दीपावली की लाइटों की सोल्डरिंग करते हुए “लोकल फॉर वोकल” के मंत्र को साकार रूप दिया। उन्होंने कहा कि “महिलाएँ अब केवल उपभोक्ता नहीं, बल्कि उत्पादक और उद्यमी बन रही हैं कृ यही आत्मनिर्भर भारत की असली तस्वीर है।” मुख्यमंत्री ने दीपावली पर महिलाओं द्वारा निर्मित अधिक से अधिक उत्पाद खरीदने का आह्वान किया।
मुख्यमंत्री ने कृषि आधारित गतिविधियों की सराहना करते हुए महिलाओं के साथ ओखल में धान कूटने की प्रक्रिया में भी सहयोग किया। उन्होंने कहा कि पारंपरिक कृषि पद्धतियाँ और हस्तनिर्मित खाद्य पदार्थ आज स्वास्थ्य, पर्यटन और ग्रामीण अर्थव्यवस्था से सीधे जुड़ रहे हैं। उन्होंने इस दिशा में महिलाओं के योगदान को प्रदेश की ग्रामीण अर्थव्यवस्था की रीढ़ बताया।
कार्यक्रम के दौरान मुख्यमंत्री ने स्थानीय व्यंजनों का स्वाद लिया और महिला समूहों द्वारा तैयार उत्पादों की भूरि-भूरि प्रशंसा की। उन्होंने कहा कि आने वाले समय में उत्तराखण्ड के हर जिले में ऐसे उत्सवों के माध्यम से महिलाओं के उत्पादों को मार्केट लिंक उपलब्ध कराया जाएगा।
मुख्यमंत्री ने महिला एवं बाल विकास विभाग द्वारा संचालित ‘महालक्ष्मी किट’ का वितरण लाभार्थी महिलाओं को किया। इसके पश्चात् उन्होंने बच्चों को अपने हाथों से बाल भोग खिलाया और उनसे आत्मीय बातचीत की। मुख्यमंत्री ने कहा कि “हर बच्चा स्वस्थ और शिक्षित हो कृ यही सशक्त समाज की पहली शर्त है।” उन्होंने आंगनबाड़ी कार्यकर्त्रियों और सहायिकाओं के योगदान की सराहना करते हुए कहा कि वे जमीनी स्तर पर पोषण अभियान और प्रारंभिक शिक्षा को सफल बनाने की सबसे मजबूत कड़ी हैं।
महिलाओं द्वारा संचालित लौह उद्योग स्टाल पर मुख्यमंत्री श्री धामी ने स्वयं चरखा चलाया, भट्टी गर्म की और लौह उत्पाद निर्माण की प्रक्रिया में सहभागिता की। उन्होंने कहा कि यह क्षेत्र भी महिलाओं की तकनीकी दक्षता और आत्मनिर्भरता का उदाहरण बन सकता है।
मुख्यमंत्री ने कहा कि राज्य सरकार महिला समूहों को सामूहिक उद्यमों, उत्पाद निर्माण, परिवहन सेवाओं और हस्तशिल्प क्षेत्रों में आगे बढ़ाने के लिए हर संभव वित्तीय, तकनीकी और विपणन सहयोग प्रदान कर रही है।
उन्होंने कहा कि “महिलाओं के सशक्तिकरण से ही राज्य सशक्त होगा। जब बहनें आत्मनिर्भर होंगी, तभी उत्तराखण्ड आत्मनिर्भर बनेगा।”
धामी ने कहा “नारी तू शक्ति है, नारी तू सृष्टि की मुस्कान है; जब नारी सशक्त होगी, तभी उत्तराखण्ड समृद्ध होगा।” उन्होंने सभी लोगों को दीपावली पर्व की अग्रिम शुभकामनाएँ देते हुए कहा कि “महिलाएँ लक्ष्मी स्वरूपा हैं, उनके सशक्त होने से परिवार, समाज और राष्ट्र सब सशक्त होते हैं।”
प्रधानमंत्री नरेंद्र मोदी के ‘नारी तू नारायणी’ मंत्र का उल्लेख करते हुए उन्होंने कहा कि केंद्र और राज्य सरकार मातृशक्ति के कल्याण हेतु निरंतर कार्यरत हैं। उज्ज्वला, जन धन, आयुष्मान भारत, प्रधानमंत्री आवास, बेटी बचाओदृबेटी पढ़ाओ तथा नारी शक्ति वंदन अधिनियम जैसी योजनाओं से महिलाओं को सशक्त बनाया गया है।
उन्होंने कहा प्रदेश में लगभग 70 हजार स्वयं सहायता समूहों के माध्यम से 5 लाख से अधिक महिलाएँ स्वरोजगार से जुड़ी हैं, जिनमें 1.65 लाख ‘लखपति दीदी’ बन चुकी हैं।
मुख्यमंत्री ने कहा कि सरकार महिलाओं के लिए सरकारी सेवाओं में 30 प्रतिशत आरक्षण लागू कर चुकी है तथा समान नागरिक संहिता लागू कर महिलाओं के अधिकारों की रक्षा का ऐतिहासिक कार्य किया गया है।
मुख्यमंत्री ने कहा कि राज्य सरकार युवाओं, माताओं और बहनों के सम्मान, सुरक्षा और स्वावलंबन के लिए पूर्णतः समर्पित है। उन्होंने मातृशक्ति से आह्वान किया कि वे ‘लोकल फॉर वोकल’ के मंत्र को जन आंदोलन बनाकर आत्मनिर्भर उत्तराखण्ड के निर्माण में सहभागी बनें।
कार्यक्रम में दर्जा राज्य मंत्री श्याम नारायण पांडे, जिला अध्यक्ष गोविंद सामंत, प्रदेश महामंत्री मुकेश कलखुड़िया, जिला पंचायत अध्यक्ष आनंद अधिकारी, ब्लॉक प्रमुख अंचला बोहरा, जिला पंचायत सदस्य सरस्वती चंद, नगर पालिका अध्यक्ष चंपावत प्रेमा पांडे, टनकपुर नगर पालिका अध्यक्ष विपिन कुमार, बनबसा नगर पंचायत अध्यक्ष रेखा देवी, जिलाधिकारी श्री मनीष कुमार, पुलिस अधीक्षक अजय गणपति, मुख्य विकास अधिकारी डॉ० जी एस खाती सहित विभिन्न जनप्रतिनिधि, विभागीय अधिकारी, गणमान्य नागरिक व हजारों की संख्या में लोग मौजूद रहे।
legal steroids for muscle mass
References:
code.kfw.net
lee priest steroids
References:
https://clone-deepsound.paineldemonstrativo.com.br
**mitolyn**
mitolyn a nature-inspired supplement crafted to elevate metabolic activity and support sustainable weight management.
**yusleep**
yusleep is a gentle, nano-enhanced nightly blend designed to help you drift off quickly, stay asleep longer, and wake feeling clear.
**zencortex**
zencortex contains only the natural ingredients that are effective in supporting incredible hearing naturally.
**breathe**
breathe is a plant-powered tincture crafted to promote lung performance and enhance your breathing quality.
Greetings! Quick question that’s entirely off topic.
Do you know how to make your site mobile friendly?
My web site looks weird when browsing from my iphone4. I’m trying to find a theme or
plugin that might be able to fix this issue. If you have any recommendations, please
share. Thank you!
Peptides that exhibit enzymatic or hormonal activities are regulatory factors and desirable therapeutic medicine due
to their excessive goal specificity and minimal unwanted facet effects.
Unfortunately, these drugs are vulnerable to enzymatic
degradation, resulting in their speedy elimination and thereby demanding frequent dosage.
Structurally modified types of some peptide medication have proven enhanced
pharmacokinetics, enhancing their oral bioavailability. Right
Here, we focus on a novel glycomimetic method to switch lysine residues in peptides.
Antimicrobial peptides act through membrane disruption, initiated by
electrostatic interactions and hydrogen bonding. Preferential affinity of such peptides for
microbial membranes (typically negatively charged) somewhat than mammalian membranes (neutral) is attributed to their cationic nature.
Giuliani et al. reviewed proposed disruption mechanisms
intimately, together with the barrel-stave, toroidal, aggregate channel, and carpet mechanisms [3].
Charnley et al. discovered that the cationic lysine residue in Ac-KPdV-NH2 is not essential
for antimicrobial activity [19]. Alternative of lysine with alanine within the sequence (Ac-APdV-NH2) did not affect the activity such that a general Ac-XPdV-NH2 or Ac-XPV-NH2 sequence was proposed.
Modification of H-KPV-NH2 on the lysine residue is due to this fact not expected to intervene with the antimicrobial activity of
the molecule and can be utilized to reinforce the peptide’s solubility and
amphipathic properties. Decreasing irritation by way of pathway modulation quite than broad immunosuppression is an enormous research development.
This minimal sequence retains the anti-inflammatory properties of the father or mother hormone with out
pigmentary results. It acts on important intracellular signaling pathways such as NF-κB and MAPK, inactivates inflammatory pathways after entering the cell, and
reduces inflammation to advertise therapeutic. KPV enters cells through PepT1, interacts with these pathways, and exerts anti-inflammatory effects.
After mobile uptake, KPV affects the following synthesis of cytokines
by influencing gene expression downstream of these signaling pathways.
The higher dose of KPV (100 μM) used in our in vivo studies was primarily based on previous research using α-MSH to treat experimental
colitis (28, 29) and was chosen to increase the probabilities of KPV to reach mouse colon.
As the proline residue places an angle within the KPV peptide, complimentary interactions may happen between one,
two or all three residues in a number of potential orientations.
This mannequin cannot, nevertheless, explain the obvious specificity of KPV for the NFκB pathway as the short peptide sequence would
presumably favour a quantity of non-specific targets.
An various hypothesis predicts that the sequence of KPV will specify its actions to a
molecule in the NFκB activation pathway. KPV displays
the elemental options of a minimal nuclear localisation sequence (NLS).
Although NLS sequences are variable, key features embrace
a cluster of positively charged residues (e.g. K-K/R-X-K/R for monopartite NLSs; [12]), usually preceded by a helix breaking residue similar to P.
Once free from its inhibitor, IκBα, the p50 and p65RelA subunits of the NFκB heterodimer migrate
to the nucleus by binding to the N and C-termini of importin-α3 (Imp-α3) respectively [14].
Their distinct however overlapping mechanisms make them a promising pair
in regenerative analysis and inflammatory recovery studies (Watson).
However, complete medical trials analyzing the synergistic
effects of those peptides in combination are limited, underscoring the need for additional analysis.
A chemotherapy-induced oral mucositis rat mannequin was induced by a modified protocol based mostly on a previously
established methodology.34 Briefly, SD rats received 30
mg kg−1 5-FU intraperitoneally (ip) on days 1, three
and 5 earlier than acetic acid insult. Subsequently, on day 6, a 6 mm diameter filter
paper disk soaked with 30% acetic acid was used to create an ulcerated
area on the gingival mucosa, and all the rats had been treated with this for
45 s. PeptideGurus is a quantity one supplier of American-made
research peptides, offering top-quality products at competitive prices.
With a give consideration to excellence and customer service, they guarantee a secure and convenient
ordering process with international shipping.
KPV offers more targeted anti-inflammatory motion, enhances peptides like BPC-157 which assist tissue regeneration, and is very efficient in epithelial (gut and skin) fashions.
KPV peptide has also proven promise in transdermal functions, notably for pores and skin health and inflammation. A research on the transdermal iontophoretic supply of KPV demonstrated the peptide’s capacity to cross microporated human pores and skin efficiently.
In one detailed lab study, researchers designed several small peptides, together with ones based mostly on components of KPV.
They examined how well these peptides could battle germs, and the outcomes
were fairly promising. When your physique is injured or irritated, it sends out
chemical messengers that begin irritation. But sometimes, the body overreacts—and that leads to persistent
issues like eczema, psoriasis, or gut issues.
The availability of high-purity KPV peptide from dependable suppliers
is crucial for harnessing these advantages. KPV, brief for Lysine–Proline–Valine, is a
naturally occurring tripeptide with potent anti-inflammatory and immune-modulating properties.
With KPV peptide remedy, you’ll be able to expertise benefits corresponding
to reduced intestine inflammation, improved intestinal barrier operate, accelerated wound therapeutic, and enhanced pores and
skin health—without compromising your immune system.
KPV peptide inhibits inflammatory pathways and reduces pro-inflammatory cytokine production in mucosal and immune cells.
References:
git.westeros.fr
KPV is an thrilling, comparatively new tripeptide made up of Lysine,
Proline, and Valine, known for its potent anti-inflammatory and
immunomodulating results. As an alpha melanocyte-stimulating hormone (Alpha-MSH),
KPV exerts its results inside cells, serving to to regulate inflammation and immune responses.
At TRT MD, KPV is used to deal with a wide selection of conditions, significantly these associated to autoimmune and inflammatory problems, corresponding
to Crohn’s disease, IBS, and colitis. Pathogenesis of persistent inflammatory autoimmune ailments by lowering continuous inflammation and
supporting immunity. Individuals with chronic irritation or autoimmune diseases typically exhibit considerably lower
levels of Tα-1 of their blood.
At the 3h time point, the medium was changed with equivalent medium containing 10μM 5-bromo-2’-deoxyuridine (BrdU).
Cells have been allowed to include the BrdU for half-hour
after which they were fixed, the DNA was denatured,
then probed utilizing 2μg.ml-1 anti-BrdU-Fluorescein antibody (Roche).
The nuclei have been counterstained with 5μM DRAQ5 and the slides had been imaged
using an LSM 510 confocal microscope. The number of S-phase cells
in every field of view was determined by calculating the number of BrdU constructive nuclei as
a percentage of the total variety of nuclei within the field of view.
These findings underscore KPV’s therapeutic promise
in managing various forms of wounds, from acute accidents to persistent ulcers, reducing scar prominence
seems. One of essentially the most promising elements of KPV
peptide injection is its potential in dermatological applications.
The peptide has shown efficacy in treating pores and skin situations such as psoriasis and pimples by lowering inflammation and
accelerating the therapeutic course of. Its ability to reinforce skin well being extends beyond cosmetic benefits, offering
therapeutic aid for patients suffering from chronic pores and skin problems.
This has led to increased interest in KPV as a versatile remedy choice in each medical
and aesthetic dermatology. Research surrounding KPV peptide
is still evolving, however early studies have demonstrated its effectiveness in treating numerous inflammatory and
immune-mediated circumstances.
Further research has explored the broader spectrum of KPV’s antimicrobial effects, together with its potential against fungal pathogens.
The peptide has shown activity towards Candida species,
that are widespread culprits in fungal infections in people.
This broad-spectrum activity makes KPV a promising candidate for
further growth into a therapeutic agent [R].
KPV peptide, consisting of the amino acids lysine, proline, and valine,
is a tripeptide spinoff of the hormone alpha-melanocyte-stimulating
hormone (α-MSH). It has gained interest in scientific
analysis due to its anti-inflammatory and immunomodulatory properties.
This is important as a end result of oxidative stress has been linked
with numerous persistent circumstances, together with cardiovascular diseases and neurodegenerative issues.
KPV has additionally been shown to minimize back the irritation that normally results in keloids or hypertrophic scars.
For example, one animal study discovered that
KPV aided in the restoration of animals affected by a
stroke. In specific, a quantity of research have reported success in providing KPV
before and during ischemia, which is when blood flow is reduced
to the brain. It happens naturally in the body, specifically in an alpha-MSH hormone, making it an alpha-melanocyte-stimulating
hormone.
As with any dietary product, people involved on this ingredient
are inspired to consult a professional healthcare professional and evaluate obtainable research to find out its relevance to their wellness objectives.
Some bodybuilders combine two varieties for a double boost—inject for muscles, cream for patches
on your pores and skin. Pre-existing points together with
your intestine, liver, or kidneys may imply you process KPV in another way.
All The Time speak to a healthcare supplier in case
you have questions about how dietary supplements fit your well being.
Many bodybuilders discover less swelling in sore spots after a tough fitness center session.
KPV blocks a key irritation pathway, so it helps your muscular tissues bounce
again without the side effects linked to widespread steroids.
This selective method to immune modulation signifies that KPV peptide can help manage
irritation while allowing the immune system to remain lively and
prepared to struggle infections. More studies are wanted to judge KPV peptide therapy for specific experimental situations.
Additional analysis will refine our understanding of KPV and optimize
its use in peptide remedy research for varied well being issues.
Even nanomolar concentrations of KPV have been proven to inhibit key inflammatory pathways in analysis fashions, so it’s potent.
Utilizing specialized nanoparticle techniques to ship
KPV has further increased its effectiveness in colonic irritation. These
findings show KPV’s potential in targeting IBD in experimental research.
By focusing on the underlying inflammatory processes,
KPV injections may provide a novel strategy to treatment, lowering the reliance on conventional medicines that often include
vital side effects. As research continues, the scope of KPV’s functions
is expected to expand, highlighting its potential as a strong software in trendy medicine.
While analysis in this area remains to be in its early levels,
there’s rising curiosity within the potential use of KPV peptide to deal with neurodegenerative ailments
like Alzheimer’s and Parkinson’s illness.
The world of peptides is vast and ever-expanding, providing new
avenues for integrative medicine and personalized healthcare.
BPC-157 and KPV stand out as two exceptional compounds with the potential to revolutionize the
administration of GI issues and MCAS. While their individual
benefits are compelling, their mixed application holds even larger
promise, hinting at a future the place focused peptide therapies might
turn into a cornerstone of integrative drugs. KPV is part of the melanocortin peptide household, which helps control immune response, inflammation, and skin pigmentation. One Other study
found that KPV accelerates corneal wound therapeutic, with treated corneas
fully therapeutic inside 60 hours, in comparison with slower healing in the placebo
group. The healing seems linked to nitric oxide (NO) exercise, as its results have been blocked
by a nitric oxide synthase inhibitor (l-NAME).
Direct Peptides offers various formulations together with 2 mg vials, nasal
sprays in 15ml and 30ml bottles, pre-mixed peptide pens, and stacks for mixed analysis functions.
These numerous choices cater to a variety of experimental requirements.
Made from a blend of citrus and palm fruit extracts,
it’s been studied for the way it influences ldl
cholesterol.
References:
https://quickdatescript.com/
**prostadine**
prostadine is a next-generation prostate support formula designed to help maintain, restore, and enhance optimal male prostate performance.
**pinealxt**
pinealxt is a revolutionary supplement that promotes proper pineal gland function and energy levels to support healthy body function.
**energeia**
energeia is the first and only recipe that targets the root cause of stubborn belly fat and Deadly visceral fat.
**prostabliss**
prostabliss is a carefully developed dietary formula aimed at nurturing prostate vitality and improving urinary comfort.
**boostaro**
boostaro is a specially crafted dietary supplement for men who want to elevate their overall health and vitality.
**potentstream**
potentstream is engineered to promote prostate well-being by counteracting the residue that can build up from hard-water minerals within the urinary tract.